{"product_id":"leuco-exosh","title":"Leuco-Exo(SH) | Microbial Exosome \/ Extracellular Vesicles","description":"\u003cstyle\u003e.ch-leuco-description{font:inherit;color:inherit;line-height:1.7;max-width:100%;}.ch-leuco-description *{box-sizing:border-box;}.ch-leuco-description .hero,.ch-leuco-description .section{background:transparent;border:1px solid currentColor;border-color:color-mix(in srgb,currentColor 15%,transparent);border-radius:8px;padding:18px;margin-bottom:22px;}.ch-leuco-description h2{font-family:inherit;color:inherit;font-size:1.35em;line-height:1.4;margin:0 0 16px;padding-bottom:10px;border-bottom:1px solid currentColor;border-color:color-mix(in srgb,currentColor 20%,transparent);}.ch-leuco-description h3{font-family:inherit;color:inherit;font-size:1.1em;margin:20px 0 10px;}.ch-leuco-description p{margin:0 0 14px;}.ch-leuco-description .hero-badge{font-size:.85em;font-weight:600;color:inherit;margin-bottom:14px;}.ch-leuco-description .hero h2 span,.ch-leuco-description .stat,.ch-leuco-description strong{color:inherit;}.ch-leuco-description .stat{font-weight:700;}.ch-leuco-description .inci-box{background:transparent;border-left:3px solid currentColor;padding:12px;margin:16px 0;overflow-wrap:anywhere;}.ch-leuco-description .benefits-grid{display:grid;grid-template-columns:1fr;gap:12px;}.ch-leuco-description .benefit-card{background:transparent;border:1px solid currentColor;border-color:color-mix(in srgb,currentColor 15%,transparent);border-radius:6px;padding:14px;}.ch-leuco-description .benefit-card strong{display:block;margin-bottom:6px;}.ch-leuco-description .benefit-card span{display:block;}.ch-leuco-description .table-wrap{overflow-x:auto;}.ch-leuco-description table{width:100%;border-collapse:collapse;font:inherit;background:transparent;color:inherit;}.ch-leuco-description th,.ch-leuco-description td{background:transparent;color:inherit;text-align:left;padding:10px;border-bottom:1px solid currentColor;border-color:color-mix(in srgb,currentColor 15%,transparent);vertical-align:top;overflow-wrap:anywhere;}.ch-leuco-description th{width:35%;}.ch-leuco-description .applications-list{display:flex;flex-wrap:wrap;gap:8px;}.ch-leuco-description .application-tag{color:inherit;background:transparent;border:1px solid currentColor;border-color:color-mix(in srgb,currentColor 20%,transparent);padding:5px 10px;border-radius:4px;font-size:.9em;}.ch-leuco-description .faq-item{padding:14px 0;border-bottom:1px solid currentColor;border-color:color-mix(in srgb,currentColor 15%,transparent);}.ch-leuco-description .faq-q{font-weight:600;margin-bottom:6px;}.ch-leuco-description .disclaimer{background:transparent;color:inherit;padding:16px;border:1px solid currentColor;border-color:color-mix(in srgb,currentColor 15%,transparent);font-size:.9em;border-radius:6px;}.ch-leuco-description .disclaimer strong{display:block;margin-bottom:8px;}@media(min-width:900px){.ch-leuco-description .benefits-grid{grid-template-columns:repeat(2,minmax(0,1fr));}}@media(max-width:600px){.ch-leuco-description .hero,.ch-leuco-description .section{padding:12px;}.ch-leuco-description th,.ch-leuco-description td{padding:8px;}}\u003c\/style\u003e\u003cdiv class=\"ch-leuco-description\"\u003e\n\u003cdiv class=\"hero\"\u003e\n\u003cdiv class=\"hero-badge\"\u003eGFC Life Sciences · Microbial Exosome Technology\u003c\/div\u003e\n\u003ch2\u003eLeuco-Exo(SH) \u003cspan\u003eMicrobial Extracellular Vesicle\u003c\/span\u003e for Hair \u0026amp; Skin\u003c\/h2\u003e\n\u003cp class=\"hero-lead\"\u003eBring next-generation exosome science to your cosmetic formulations. Leuco-Exo(SH) delivers \u003cstrong\u003eLeuconostoc extracellular vesicles\u003c\/strong\u003e isolated via GFC's proprietary Hybrid-Exotech method. With \u003cspan class=\"stat\"\u003e~118.2 nm\u003c\/span\u003e particles, \u003cspan class=\"stat\"\u003e7 hair-growth-factor\u003c\/span\u003e response data, and a \u003cspan class=\"stat\"\u003e12-week human hair-density study\u003c\/span\u003e, this is a specialised active for professional scalp and skincare development.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"section\"\u003e\n\u003ch2\u003eWhat is Leuco-Exo(SH)?\u003c\/h2\u003e\n\u003cp\u003eLeuco-Exo(SH) is GFC Life Sciences' microbial extracellular vesicle ingredient, isolated from its proprietary \u003cstrong\u003eLeuconostoc GFC1203H\u003c\/strong\u003e strain using the Hybrid-Exotech method. It is supplied as a colourless, clear liquid in a water-based carrier.\u003c\/p\u003e\n\u003cdiv class=\"inci-box\"\u003e\n\u003cstrong\u003eINCI:\u003c\/strong\u003e Water, Butylene Glycol, 1,2-Hexanediol, Leuconostoc Extracellular Vesicles\u003c\/div\u003e\n\u003cp\u003eThis is a \u003cstrong\u003ecosmetic raw material\u003c\/strong\u003e for professional formulators. It is not a finished consumer product.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"section\"\u003e\n\u003ch2\u003eThe Science Behind It\u003c\/h2\u003e\n\u003ch3\u003eWhat Are Exosomes?\u003c\/h3\u003e\n\u003cp\u003eExtracellular vesicles (exosomes) are nanoscale membrane-bound particles (approximately 50–200 nm) released by cells. They carry proteins, nucleic acids, DNA, mRNA, and lipids, functioning as messengers that transmit genetic information between cells. Their natural roles include tissue growth, regeneration, and immune regulation.\u003c\/p\u003e\n\u003ch3\u003eThe Leuco-Exo Difference\u003c\/h3\u003e\n\u003cp\u003eLeuco-Exo is specifically \u003cstrong\u003emicrobe-derived\u003c\/strong\u003e. GFC's research began with scalp sampling across age groups (n=80), leading to the identification of a lactic acid bacterial strain associated with people in their teens and twenties: \u003cstrong\u003eLeuconostoc GFC1203H\u003c\/strong\u003e. This strain was identified through 16S rDNA sequencing and deposited under patent \u003cstrong\u003eKCTC14077BP\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cp\u003eThe vesicles feature a \u003cstrong\u003ephospholipid-bilayer structure\u003c\/strong\u003e (the same architecture as human cell membranes) and have been characterised by Nanoparticle Tracking Analysis (NTA) at approximately \u003cstrong\u003e118.2 nm\u003c\/strong\u003e. At this scale, they are \u003cstrong\u003e184–462 times smaller than skin pores\u003c\/strong\u003e, supporting efficient delivery to target cells.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"section\"\u003e\n\u003ch2\u003eKey Benefits \u0026amp; Research Data\u003c\/h2\u003e\n\u003cdiv class=\"benefits-grid\"\u003e\n\u003cdiv class=\"benefit-card\"\u003e\n\u003cstrong\u003eNanoscale Characterisation\u003c\/strong\u003e \u003cspan\u003e~118.2 nm particle size confirmed by NTA\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"benefit-card\"\u003e\n\u003cstrong\u003eHair Growth Factors (In Vitro)\u003c\/strong\u003e \u003cspan\u003eIncreased all 7 assessed hair-growth factors with Leuco-Exo treatment\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"benefit-card\"\u003e\n\u003cstrong\u003eHuman Hair Density Study\u003c\/strong\u003e \u003cspan\u003e14.54% improvement at 12 weeks (Korea Dermatology Research Institute)\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"benefit-card\"\u003e\n\u003cstrong\u003eSkin Regeneration (In Vitro)\u003c\/strong\u003e \u003cspan\u003e~50% greater wound-healing response vs. control\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"benefit-card\"\u003e\n\u003cstrong\u003eCell Survival (In Vitro)\u003c\/strong\u003e \u003cspan\u003eInhibited cell death and increased growth rate in apoptosis assay\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"benefit-card\"\u003e\n\u003cstrong\u003eAntioxidant Activity\u003c\/strong\u003e \u003cspan\u003eGreater free-radical scavenging than the type strain\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"benefit-card\"\u003e\n\u003cstrong\u003eScalp Health Support\u003c\/strong\u003e \u003cspan\u003eInhibits bacteria associated with dandruff and scalp inflammation\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"benefit-card\"\u003e\n\u003cstrong\u003eKGF Expression\u003c\/strong\u003e \u003cspan\u003eKeratinocyte Growth Factor (KGF) mRNA expression in hair-growth research\u003c\/span\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"section\"\u003e\n\u003ch2\u003eSpecifications\u003c\/h2\u003e\n\u003cdiv class=\"table-wrap\"\u003e\u003ctable\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eProduct\u003c\/th\u003e\n\u003ctd\u003eLeuco-Exo(SH)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eManufacturer\u003c\/th\u003e\n\u003ctd\u003eGFC Life Sciences Co., Ltd.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eINCI\u003c\/th\u003e\n\u003ctd\u003eWater, Butylene Glycol, 1,2-Hexanediol, Leuconostoc Extracellular Vesicles\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eSource Strain\u003c\/th\u003e\n\u003ctd\u003eLeuconostoc GFC1203H\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eStrain Deposit\u003c\/th\u003e\n\u003ctd\u003eKCTC14077BP\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eIsolation Method\u003c\/th\u003e\n\u003ctd\u003eHybrid-Exotech\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eParticle Size\u003c\/th\u003e\n\u003ctd\u003e~118.2 nm (NTA confirmed)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eAppearance\u003c\/th\u003e\n\u003ctd\u003eColourless, clear liquid\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eOdour\u003c\/th\u003e\n\u003ctd\u003eSlightly characteristic\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003epH\u003c\/th\u003e\n\u003ctd\u003e5.00 – 9.00\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eSpecific Gravity\u003c\/th\u003e\n\u003ctd\u003e0.990 – 1.010\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eRefractive Index\u003c\/th\u003e\n\u003ctd\u003e1.335 – 1.345\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eRecommended Usage\u003c\/th\u003e\n\u003ctd\u003e1.0 – 4.0%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eStorage\u003c\/th\u003e\n\u003ctd\u003eStore in a cool, dry place in a well-closed container, protected from light\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eShelf Life\u003c\/th\u003e\n\u003ctd\u003e2 years from date of production\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"section\"\u003e\n\u003ch2\u003eRecommended Applications\u003c\/h2\u003e\n\u003cp\u003eLeuco-Exo(SH) is ideal for formulators developing advanced scalp and skincare products:\u003c\/p\u003e\n\u003cdiv class=\"applications-list\"\u003e\n\u003cspan class=\"application-tag\"\u003eScalp Serums\u003c\/span\u003e \u003cspan class=\"application-tag\"\u003eHair Tonics\u003c\/span\u003e \u003cspan class=\"application-tag\"\u003eHair Growth Formulations\u003c\/span\u003e \u003cspan class=\"application-tag\"\u003eFacial Serums\u003c\/span\u003e \u003cspan class=\"application-tag\"\u003eAmpoules\u003c\/span\u003e \u003cspan class=\"application-tag\"\u003eSkin Repair Creams\u003c\/span\u003e \u003cspan class=\"application-tag\"\u003eAnti-Aging Skincare\u003c\/span\u003e \u003cspan class=\"application-tag\"\u003eSkin-Conditioning Products\u003c\/span\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"section\"\u003e\n\u003ch2\u003eUsage \u0026amp; Formulation Notes\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eRecommended concentration:\u003c\/strong\u003e 1.0 – 4.0% of the supplied Leuco-Exo(SH) ingredient.\u003c\/p\u003e\n\u003cp\u003eAlways refer to current GFC Life Sciences technical documentation when developing your finished cosmetic formulation. This is a raw material; final formulation stability, compatibility, and efficacy must be evaluated by a qualified cosmetic chemist for your specific product.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"section\"\u003e\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003cdiv class=\"faq-item\"\u003e\n\u003cdiv class=\"faq-q\"\u003eWhat is the INCI name?\u003c\/div\u003e\n\u003cdiv class=\"faq-a\"\u003eWater, Butylene Glycol, 1,2-Hexanediol, Leuconostoc Extracellular Vesicles.\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"faq-item\"\u003e\n\u003cdiv class=\"faq-q\"\u003eIs this human stem-cell exosome?\u003c\/div\u003e\n\u003cdiv class=\"faq-a\"\u003eNo. Leuco-Exo contains microbial extracellular vesicles derived from Leuconostoc GFC1203H, isolated using GFC's proprietary Hybrid-Exotech method.\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"faq-item\"\u003e\n\u003cdiv class=\"faq-q\"\u003eWhat makes this ingredient distinctive?\u003c\/div\u003e\n\u003cdiv class=\"faq-a\"\u003eIts proprietary scalp-derived microbial strain (GFC1203H), ~118.2 nm NTA-characterised particles, and research spanning hair-growth-factor responses, human hair density, and skin-cell regeneration assays.\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"faq-item\"\u003e\n\u003cdiv class=\"faq-q\"\u003eWhat did the human hair study find?\u003c\/div\u003e\n\u003cdiv class=\"faq-a\"\u003eThe Korea Dermatology Research Institute study reported test-group hair-density improvements of 9.41% at week 4, 12.02% at week 8, and 14.54% at week 12.\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"faq-item\"\u003e\n\u003cdiv class=\"faq-q\"\u003eWhat usage range is recommended?\u003c\/div\u003e\n\u003cdiv class=\"faq-a\"\u003eGFC recommends 1.0 – 4.0% of the supplied ingredient in finished cosmetic formulations.\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"faq-item\"\u003e\n\u003cdiv class=\"faq-q\"\u003eIs this the same as Salmon PDRN?\u003c\/div\u003e\n\u003cdiv class=\"faq-a\"\u003eNo. Leuco-Exo is a microbial extracellular-vesicle ingredient. Salmon PDRN is a different ingredient category (DNA fragments derived from salmon). They are not the same and are not interchangeable.\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"faq-item\"\u003e\n\u003cdiv class=\"faq-q\"\u003eIs a COA available?\u003c\/div\u003e\n\u003cdiv class=\"faq-a\"\u003eYes. COA is available upon request.\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"disclaimer\"\u003e\n\u003cstrong\u003eDisclaimer\u003c\/strong\u003e For professional external cosmetic use only. Not for injection or ingestion. Research summaries are based on GFC Life Sciences' supplied material and relate to the stated test conditions; they do not guarantee identical performance in every finished cosmetic. No guaranteed hair-regrowth, hair-loss-treatment, or wound-healing claims are made. Cosmeti Hub supplies ingredients, not complete formulations. Consult a qualified cosmetic chemist for formulation guidance and finished-product assessment.\u003c\/div\u003e\n\u003c\/div\u003e","brand":"GFC Life Science","offers":[{"title":"1.00 Kg","offer_id":67666996625684,"sku":null,"price":178820.0,"currency_code":"PKR","in_stock":true},{"title":"500.00 Gram","offer_id":67666996658452,"sku":null,"price":89410.0,"currency_code":"PKR","in_stock":true},{"title":"250.00 Gram","offer_id":67666996691220,"sku":null,"price":46880.0,"currency_code":"PKR","in_stock":true},{"title":"100.00 Gram","offer_id":67666996723988,"sku":null,"price":19530.0,"currency_code":"PKR","in_stock":true},{"title":"50.00 Gram","offer_id":67666996756756,"sku":null,"price":10160.0,"currency_code":"PKR","in_stock":true},{"title":"25.00 Gram","offer_id":67666996789524,"sku":null,"price":5470.0,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0771\/7473\/5124\/products\/CosmetiHubProductDefault_afae890c-6848-43ae-9a74-a71518ef00e6.png?v=1754510896","url":"https:\/\/cosmetihub.com\/products\/leuco-exosh","provider":"Cosmeti Hub | Cosmetic Raw Materials \u0026 Ingredients Supplier in Pakistan","version":"1.0","type":"link"}